Real Valladolid will look to claim the major scalp of Barcelona when the teams meet at Estadio Municipal Jose Zorrilla on Tuesday 22 December 2020.

Tottenham Hotspur will take on Leicester City in an English Premier League match at the Tottenham Hotspur Stadium on December 20

CA Osasuna will lock horns with Villarreal in a Spanish La Liga match at the Estadio El Sadar on December 19. 

Southampton will be aiming to add to Arsenal's growing list of problems when the two teams meet in a 2020-21 English Premier League this week. 

Lazio will be away to Benevento in an Italian Serie A match at the Stadio Ciro Vigorito on December 15.

Kubrat Pulev will finally get his chance to face Unified WBA (Super), IBF, WBO, and IBO world champion Anthony Joshua on December 12.